Hydroxyurea Could Be a Good Clinically Relevant Iron Chelator
نویسندگان
چکیده
منابع مشابه
Hydroxyurea Could Be a Good Clinically Relevant Iron Chelator
Our previous study showed a reduction in serum ferritin of β-thalassemia patients on hydroxyurea therapy. Here we aimed to evaluate the efficacy of hydroxyurea alone and in combination with most widely used iron chelators like deferiprone and deferasirox for reducing iron from experimentally iron overloaded mice. 70 BALB/c mice received intraperitonial injections of iron-sucrose. The mice were ...
متن کاملCould Hair Loss be a Relevant Symptom Associated with Chikungunya?
Chikungunya (CHIK) is a disease caused by a mosquito-borne alphavirus (the mosquitos Aedes aegypti or Aedes albopictus). The chikungunya virus (CHIKV) is present all over the world. Several clinical symptoms have been associated with CHIK including hair loss. The aim of this review is to present some symptoms related to CHIK, tissues and organs targeted by the CHIKV and to suggest how the infec...
متن کاملWhat could be more practical than a good interpretation ?
Quantum mechanics is more than the derivation of straightforward theorems about vector spaces, Hilbert spaces and functional analysis. In order to be applicable to experiment and technology, those theorems need interpretation and meaning. Interpretation is to the formalism what a scaffolding in architecture and building construction is to the completed
متن کاملIron chelator drugs in thalassemia,a review article
Abstract Thalassemia syndromes are the most common inherited hemoglobinopathies in the world characterized by various degrees of defective production of the alpha or beta globin chains. Impairment in alpha chain or beta chain synthesis leads to alpha thalassemia and beta thalassemia syndromes respectively. Iran is one of the countries located on the thalassemia belt therefore this disease is ...
متن کاملCould adult hippocampal neurogenesis be relevant for human behavior?
Although the function of adult neurogenesis is still unclear, tools for directly studying the behavioral role of new hippocampal neurons now exist in rodents. Since similar studies are impossible to do in humans, it is important to assess whether the role of new neurons in rodents is likely to be similar to that in humans. One feature of adult neurogenesis that varies tremendously across specie...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0082928